That comprises about 85 percent of women with breast cancer in this age group, the researchers noted.
(That mouthful refers to three things: that the cancer was found early, that it could bind to certain hormones and that it didn't have the HER2 receptor.) This type of breast cancer is the most common type, according to the researchers.
The findings will lead to a "fundamental change" in how the disease is treated, a leading oncologist said. "Updated results for patients with a low recurrence score of 10 or less, who were previously reported as having a 1% distant recurrence rate at 5 years in our trial, now indicate a 9-year rate of distant recurrence of approximately 3%", the authors add.
The 21-gene recurrence-score Oncotype Dx assay is one of several commercially available gene expression assays that can offer prognostic insight in hormone-receptor-positive breast cancer.
"With results of this groundbreaking study, we now can safely avoid chemotherapy in about 70 percent of patients who are diagnosed with the most common form of breast cancer", said co-author Kathy Albain, an oncologist at Loyola Medicine in a Chicago suburb.
Patients under 50 with a score of up to 15 also do not need to undergo the treatment, the research concluded.
Dr Simon Vincent, director of research at the charity Breast Cancer Now, warned more patients will have to be treated to assess how effective the therapy is.
"It's also highly significant that this outcome suggests reprogramming patients' immune cells as part of a two-pronged attack could be a viable way to treat ER-positive tumours - which could open this approach up to benefit many patients with metastatic breast cancer".
"Side effects, such as hair loss, severe pain and infertility, can be utterly devastating and linger long after they walk out the hospital doors".
"Breast cancer treatments have advanced so much that treatments can nearly be tailored for patients and this is extremely welcome news as chemotherapy is a particularly invasive treatment". Women were separated into 2 groups, one receiving only hormone therapy, the other receiving chemotherapy and hormone therapy. While trying treatment after treatment, she became a breast cancer advocate and went to California for training by Project Lead, a program run by the National Breast Cancer Coalition.
Thousands of women have been tested over the years using Oncotype DX to help determine the true effectiveness of chemo. Erring on the side of caution, doctors usually give these women chemotherapy. "In many cases, we will be able to tailor treatments to the patient and their tumor".
In a reaction via the Science Media Centre in London, immunotherapy professor Alan Melcher of The Institute of Cancer Research said the trial was "fascinating and exciting". Now only about 60 percent of US patients who could potentially benefit from it are taking the gene test, he says.
"Oncologists have been getting much smarter about dialing back treatment so that it doesn't do more harm than good", said Steven Katz, a University of MI researcher who examines medical decision-making.
But cut to the next day, he met a North Korean official at the White House and pointed out that the summit was back on track. Trump and Kim were scheduled to meet in Singapore on June 12, but the American leader walked away from the summit last month.
Paul Pogba has his starting place in France national team in question after a poor display in the last friendly against Italy . I will not remember that, but if it maybe could not be the case, it would be better".
No one on this planet can deny the fact that Johnny Depp is a flawless blend of an actor and a handsome hunk. He also stars in the upcoming Fantastic Beasts film, The Crimes of Grindelwald (in theaters November 16).
The German recorded 51 winners to reach his first round of 16 in Paris after nearly four hours of play on Court Philippe Chatrier. Today, she clinched the 21st Grand Slam match win and extended to 12-4 her win-loss record in Paris .
A Saudi woman speaking to an officer before her driving exam, at the General Department of Traffic in the capital, Riyadh. The prosecutor's statement said eight have been temporarily released , while five men and four women remain under arrest.
On Tuesday Palestinian militants fired dozens of mortar bombs and rockets into Israel from Gaza, drawing Israeli air strikes. She doesn't just capture the tragedy of the many deaths, but the triumph of life too, and its many faces, in the Gaza Strip.
There may be a ray of sunshine amidst dark stormy clouds when it comes to avoiding a massive trade war between the US and China. Speaking after the meeting, Le Maire said the European Union was poised to take counter-measures against the new US tariffs.
Draxler, Reus and Muller are set. "He will be back again from Sept", Low said. "He has not arrived in global matches yet". Germany , the reigning champions, are in World Cup group F, along with Mexico, Sweden and the Korea Republic.
You can now challenge any of your friends to an exercise competition, which will compare your tracking stats to your friends'. The Apple Watch is all about making simple actions easily accessible with a single tap or putting notifications at a glance.
Lastra said the Socialists plan to call early elections, before the legislature expires in 2020, but did not specifying a date. Spain's Socialist Party (PSOE) leader Pedro Sanchez gestures during a motion of no confidence debate at Parliament in Madrid .
Grassley (R-Iowa), the chairman of the Senate Judiciary Committee, on Monday warned Trump against considering pardoning himself . Trump's legal team is "raising all kinds of legal arguments that I think most people don't think hold water".
The House impeached Clinton in 1998, but the Senate acquitted the President, preventing his removal from office. Clinton's comments come amid a national reckoning with sexual harassment and assault in the workplace.
Germany’s Merkel to work with Italy’s populist new govt
European leaders in Brussels, already anxious about Poland and Hungary, now worry a menace to European unity from inside its core. Both parties campaigned on a policy platform that was characteristically hostile toward the European Union and the euro.
Andre Iguodala is pain-free and could return soon
Game 2 looked like a replay of last year's Finals games in Oakland, California with the Warriors winning in blowout fashion. That he is, and now the Warriors find themselves up 2-0 on the Cavaliers.